Trimsy

Weight Loss Approaches

There is no single "best" way to lose weight. The most sustainable results come from understanding your options and combining approaches that fit your life, preferences, and health situation.

Why combining approaches works best

Every method on this page has merit, and every method has limitations. Research consistently shows that the people who successfully lose weight and keep it off are those who combine multiple strategies — typically a moderate calorie deficit, adequate protein, regular exercise (especially strength training), and sustainable behavioural changes.

GLP-1 medications can be a powerful tool in this toolkit, but they're one option among many. Whether you choose medication or not, the lifestyle foundations below will determine your long-term success. Start with what resonates, build consistency, and layer in additional approaches over time.

GLP-1 Medications

Prescription medications that reduce appetite and aid weight loss

Strong evidence

How it works

GLP-1 receptor agonists (like semaglutide and tirzepatide) mimic a gut hormone that signals fullness to your brain. They slow gastric emptying, reduce appetite, and improve blood sugar regulation — making it physically easier to eat less.

Who it's best for

People with a BMI of 30+ (or 27+ with weight-related conditions) who have struggled with diet and exercise alone. Best when combined with lifestyle changes.

Pros

  • Significant average weight loss (15-25% of body weight in clinical trials)
  • Reduces food noise and cravings substantially
  • Improves metabolic health markers beyond just weight
  • Weekly injection is simple once you get used to it

Cons

  • Requires a prescription and ongoing medical supervision
  • Common side effects include nausea, especially early on
  • Expensive without insurance coverage
  • Weight regain is common if stopped without lifestyle changes in place
  • Not suitable for everyone (contraindications exist)

Getting started

Speak to your GP or a weight management specialist about whether you're a candidate. Check our medications page for a full comparison of available options.

Compare GLP-1 medications

Calorie Deficit

The fundamental principle behind all weight loss

Strong evidence

How it works

Your body uses a certain amount of energy each day (your Total Daily Energy Expenditure, or TDEE). When you consistently consume fewer calories than your TDEE, your body draws on stored energy (fat) to make up the difference. A deficit of roughly 500 calories per day leads to about 0.5kg (1lb) of fat loss per week.

Who it's best for

Everyone — this is the underlying mechanism of all weight loss regardless of method. Particularly effective for people who enjoy tracking and seeing data, and those who want flexibility in food choices.

Pros

  • Scientifically proven and universally applicable
  • No foods are off-limits — it's about total intake
  • Free to implement
  • Flexible and adaptable to any lifestyle or dietary preference
  • Easy to measure progress objectively

Cons

  • Calorie counting can become tedious or obsessive for some people
  • TDEE calculators are estimates — individual metabolism varies
  • Doesn't distinguish between food quality (a calorie is not just a calorie for health)
  • Can lead to under-eating if deficit is too aggressive
  • Hunger management is entirely on you

Getting started

Calculate your TDEE using an online calculator (search for 'TDEE calculator'), then subtract 300-500 calories. Track your food with an app like MyFitnessPal or Cronometer for at least two weeks to understand your baseline intake before making changes.

High-Protein Diet

Prioritising protein for satiety, muscle preservation, and fat loss

Strong evidence

How it works

Protein is the most satiating macronutrient — it keeps you fuller for longer per calorie consumed. It also has a higher thermic effect (your body burns more energy digesting it) and is essential for preserving lean muscle mass during weight loss. Aiming for 1.6-2.2g per kg of body weight is a common target.

Who it's best for

Anyone losing weight, especially those who are also exercising. Critical for people on GLP-1 medications where appetite is very suppressed and you need to make every bite count. Also great for people who struggle with hunger between meals.

Pros

  • Reduces hunger and cravings naturally
  • Preserves muscle mass during weight loss (crucial for metabolism)
  • Higher thermic effect means you burn more calories digesting it
  • Supports recovery from exercise
  • Relatively simple to implement — just prioritise protein at each meal

Cons

  • High-protein foods can be more expensive (meat, fish, dairy)
  • Can be harder for vegetarians/vegans (but not impossible)
  • Excessive protein without adequate fibre can cause digestive issues
  • Requires some meal planning and preparation

Getting started

Start by adding a palm-sized portion of protein to every meal and snack. Easy wins: Greek yoghurt for breakfast, chicken or beans at lunch, and eggs as a snack. Aim for at least 25-30g of protein per meal.

Intermittent Fasting

Restricting when you eat rather than what you eat

Moderate evidence

How it works

Intermittent fasting (IF) involves cycling between periods of eating and fasting. The most popular method is 16:8 (eating within an 8-hour window, fasting for 16 hours). The 5:2 method involves eating normally for 5 days and significantly reducing calories (500-600) on 2 non-consecutive days. It works primarily by helping people eat less overall.

Who it's best for

People who prefer simple rules over calorie counting, those who naturally aren't hungry in the morning, and anyone who tends to overeat in the evening. Works well for busy schedules where meal prep time is limited.

Pros

  • Simple to follow — no calorie counting required
  • Can naturally reduce overall calorie intake
  • Some evidence for metabolic benefits beyond weight loss
  • Flexible — you choose the eating window that suits your schedule
  • May improve relationship with food by reducing constant snacking

Cons

  • Can lead to overeating during the eating window
  • Not suitable for people with a history of eating disorders
  • May cause irritability, low energy, or difficulty concentrating during fasting periods
  • Social situations can be awkward (declining meals during fasting windows)
  • Not recommended during pregnancy or for people with certain medical conditions

Getting started

Try the 16:8 method first — skip breakfast and eat between 12pm and 8pm. Start gradually by pushing breakfast back by an hour each day until you reach your target window. Stay hydrated with water, black coffee, or herbal tea during the fasting period.

Strength Training for Fat Loss

Building muscle to transform your body composition

Strong evidence

How it works

Strength training (resistance exercise) builds and preserves lean muscle mass, which increases your basal metabolic rate — meaning you burn more calories at rest. During weight loss, up to 25% of weight lost can be muscle unless you actively train to prevent it. Strength training shifts the ratio toward fat loss and creates the 'toned' look most people are actually after.

Who it's best for

Everyone losing weight, but especially those on GLP-1 medications where rapid weight loss increases muscle loss risk. Also ideal for people who have been focused on cardio and hit a plateau, or anyone who wants to improve body composition rather than just seeing a lower number on the scale.

Pros

  • Preserves and builds metabolically active muscle tissue
  • Increases resting metabolic rate over time
  • Improves bone density, posture, and functional strength
  • Creates visible body composition changes even when the scale doesn't move
  • Boosts confidence and energy levels

Cons

  • Requires learning proper form (consider a few sessions with a trainer)
  • Scale weight may not drop as fast (muscle is denser than fat)
  • Can be intimidating for beginners
  • Needs consistency — 2-3 sessions per week minimum for results
  • Gym membership or equipment has a cost

Getting started

Start with 2-3 full-body sessions per week using compound movements: squats, deadlifts, rows, presses, and lunges. Begin with bodyweight or light weights and focus on form. A simple 3x10 (three sets of ten reps) structure works well for beginners.

View training plans

Behavioural / Habit-Based Approaches

Small changes that compound into lasting transformation

Moderate evidence

How it works

Rather than relying on willpower (which is a finite resource), habit-based approaches focus on building automatic behaviours through small, consistent changes. Techniques include habit stacking (attaching a new habit to an existing one), environment design (making healthy choices the path of least resistance), and cognitive behavioural strategies to address emotional eating patterns.

Who it's best for

People who have tried and failed with strict diets, emotional eaters, anyone who knows what to do but struggles to do it consistently, and those looking for a sustainable long-term approach rather than a quick fix.

Pros

  • Sustainable — habits become automatic and don't require willpower
  • Addresses the root causes of overeating, not just symptoms
  • Can be combined with any other approach on this list
  • No restriction or deprivation — focuses on adding good habits
  • Improves overall wellbeing, not just weight

Cons

  • Results are slower — this is a long game
  • Less structured, which doesn't suit everyone
  • May require professional support (therapist, coach) for deep-seated patterns
  • Hard to measure progress in the early stages
  • Requires honest self-reflection and patience

Getting started

Pick one small habit to start with — for example, drinking a glass of water before every meal. Do it consistently for two weeks before adding another. Use habit stacking: 'After I [existing habit], I will [new habit].' Focus on consistency over intensity.

Combined Approaches

The most effective strategy is usually a thoughtful combination

Strong evidence

How it works

No single method works optimally in isolation. The most successful long-term weight management typically combines a moderate calorie deficit, adequate protein intake, regular strength training, and behavioural strategies — with or without medication support. The key is choosing a combination that fits your life, preferences, and medical situation.

Who it's best for

Everyone, ultimately. Once you've tried individual approaches and know what works for you, combining them amplifies results. Particularly effective for people who have plateaued with a single method or those who want to optimise their approach.

Pros

  • Addresses weight loss from multiple angles simultaneously
  • More sustainable than any single extreme approach
  • Allows you to use the strengths of each method to offset the weaknesses of others
  • Flexible — adjust the combination as your needs change
  • Backed by the strongest evidence for long-term weight maintenance

Cons

  • Can feel overwhelming if you try to change everything at once
  • Requires more knowledge and self-awareness
  • Harder to pinpoint what's working and what isn't
  • Risk of overcomplicating things — simplicity still matters

Getting started

Start with a foundation of adequate protein and a moderate calorie deficit. Add strength training 2-3 times per week. Layer in one behavioural change at a time. If considering medication, discuss with your doctor how it fits into your overall plan. Don't try to do everything at once — build up over 4-8 weeks.

Not sure which approach is right for you?

Get our free guide comparing all weight loss methods with a personalised recommendation quiz.

Free. No spam. Unsubscribe anytime.

Important medical disclaimer

The information on this page is for general educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Weight loss affects everyone differently and what works for one person may not be appropriate for another. Always consult a qualified healthcare professional before starting any new diet, exercise programme, or medication. If you are considering GLP-1 medications or any prescription treatment, you must do so under the supervision of a licensed medical provider. Never disregard professional medical advice or delay seeking it because of something you have read on this website.